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Propoflo™ and Propoflo ™ 28
Propoflo™ and Propoflo™ 28 (propofol injectable emulsion) are injectable medications for use in dogs for induction of anesthesia, for maintenance of general anesthesia for up to 20 minutes, or for induction of general anesthesia where maintenance is provided by inhalant anesthetics.
- Delivers consistent, high quality induction
- Tailored to duration of procedure and to protocol
- No refrigeration required
- PropoFlo 28 has 28-day in-use shelf life
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- Propofol injection is an intravenous sedative hypnotic agent for use in the induction and maintenance of anesthesia.
- Intravenous injection of propofol in the dog is followed by extensive metabolism of propofol in the liver to inactive conjugates which are excreted in the urine.
- Elimination from the central compartment occurs rapidly; induction of anesthesia will usually be observed within 65-120 seconds after the beginning of propofol administration.
- The duration of anesthesia following the recommended induction doses ranges from 5.8- 6.7 minutes.
- PropoFlo should be used within 6 hours after the vial has been broached.
- PropoFlo 28 has shelf-life of 28 days after first use.
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- PropoFlo has an induction range of 2.6mg/kg–5.5 mg/kg over 30–60 seconds.
- PropoFlo 28 has an induction range of 3.2–7.6 mg/kg over 60–90 seconds.
- Dose to effect (until clinical signs show onset).
- Titrated over 60-90 seconds against the response or until clinical signs show the onset of anesthesia.
IMPORTANT SAFETY INFORMATION
Not for human use. Rare cases of self-administration have been reported, including fatalities. Exercise caution to avoid accidental self-injection. PropoFlo™ and PropoFlo™ 28 (propofol injectable emulsion) are contraindicated in dogs with known hypersensitivity to propofol or its components or when general anesthesia or sedation are contraindicated. Rapid single or repeat bolus administration (induction or maintenance) or accidental overdosage of Propflo or PropoFlo 28 may cause undesirable cardiorespiratory depression including hypotension, apnea and oxygen desaturation. When using PropoFlo or PropoFlo 28, dogs should be continuously monitored and facilities for the maintenance of patent airway, artificial ventilation and oxygen supplementation must be immediately available. Careful monitoring of the patient is necessary when using PropoFlo or PropoFlo 28 as a maintenance anesthetic due to the possibility of rapid arousal. PropoFlo and PropoFlo 28 have not been evaluated in pregnant or breeding dogs or dogs less than 10 weeks of age. Adverse reactions may include respiratory depression as evidenced by tachypnea and apnea. To avoid microbial overgrowth, PropoFlo 28 must be used within 28 days (4 weeks) of the date opened. Unused PropoFlo must be discarded within 6 hours of opening. Failure to follow aseptic handling procedures may result in microbial contamination causing fever, infection/sepsis, and/or other life threatening illness. Do not use if contamination is suspected.
For more safety information on PropoFlo, see full Prescribing Information here.
This site is intended for U.S. Animal Healthcare Professionals. The product information provided in this site is intended only for residents of the United States. The products discussed herein may not have marketing authorization or may have different product labeling in different countries. The animal health information contained herein is provided for educational purposes only and is not intended to replace discussions with an animal healthcare professional. All decisions regarding the care of a veterinary patient must be made with an animal healthcare professional, considering the unique characteristics of the patient.
PRO-00322A
United States 
